Mapping structural landscapes: isomorphic mefenamic acid and tolfenamic acid forms
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چکیده
منابع مشابه
Mefenamic acid enteropathy.
The clinical, radiological, and histological features of two patients with severe intestinal damage induced by mefenamic acid and mimicking coeliac disease are described. Symptoms rapidly reverted on withdrawal of the drug, and in one case, did not relapse during treatment with other non-steroidal anti-inflammatory drugs.
متن کاملMefenamic acid-induced bullous pemphigoid.
A 52 year old man developed bullous pemphigoid, Coombs' positive haemolytic anaemia and diarrhoea related to the use of mefenamic acid. Clinical manifestation of the bullous pemphigoid, haemolytic anaemia and diarrhoea resolved following discontinuation of the mefenamic acid. Mefenamic acid should be added to the list of agents that are known to induce bullous pemphigoid.
متن کاملSpherical Crystallization of Mefenamic Acid
*To whom all correspondence should be addressed. he quality of a solid pharmaceutical preparation is influenced by primary micromeritic characteristics such as the shape and size of drug crystals, especially when large amounts of poorly soluble drugs are formulated. To improve the dissolution rate of poorly soluble drugs, fine crystals are preferred over large crystals because they provide a gr...
متن کاملEnteritis and colitis associated with mefenamic acid.
Water intoxication causes hyponatraemia, which is responsible for the neurological dysfunction by causing intracellular overhydration. Symptoms may occur if the serum sodium concentration is less than 120 mmol/l, but the degree of brain dysfunction corresponds with the rapidity of development of the hyponatraemia. Intracellular potassium concentration is reduced, partly due to increased intrace...
متن کاملAutoimmune haemolytic anaemia and mefenamic acid therapy.
Three patients developed autoimmune haemolytic anaemia while being treated with mefenamic acid. In each case the autoimmune haemolytic anaemia was of the warm antibody gammaG type, and the antibodies had some rhesus specificity. All three patients recovered when the drug was withdrawn.Attempts to inhibit or enhance the activity of the antibody in vitro were unsuccessful.Direct antihuman globuli...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations and Advances
سال: 2017
ISSN: 2053-2733
DOI: 10.1107/s2053273317081293